A TXT-type anvi’o artifact. This artifact is typically provided by the user for anvi’o to import into its databases, process, and/or use.
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There are no anvi’o tools that generate this artifact, which means it is most likely provided to the anvi’o ecosystem by the user.
anvi-script-gen-defense-finder-models-to-hmm-directory anvi-script-hmm-to-hmm-directory
A flat text HMM that literally desribes the properties of the model and lists transition probabilities.
Such files are typically generated by the program hmmbuild
(which is a part of the HMMER package and installed in every anvi’o environment) from FASTA files of gene amino acid sequence alignments. A properly formatted hmm-file will look more or less like this:
HMMER3/f [3.3 | Nov 2019]
NAME NusB
ACC PF01029.22
DESC NusB family
LENG 133
ALPH amino
RF no
MM no
CONS yes
CS no
MAP yes
DATE Sat Apr 29 10:48:13 2023
NSEQ 63
EFFN 5.564026
CKSUM 2756372009
GA 23.1 23.1;
TC 23.1 23.1;
NC 23 23;
BM hmmbuild HMM.ann SEED.ann
SM hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
STATS LOCAL MSV -9.6745 0.71150
STATS LOCAL VITERBI -10.4604 0.71150
STATS LOCAL FORWARD -4.0120 0.71150
HMM A C D E F G H I K L M N P Q R S T V W Y
m->m m->i m->d i->m i->i d->m d->d
COMPO 2.38570 4.55521 2.97888 2.58191 3.42062 3.17155 3.83378 2.76365 2.65171 2.28201 3.70599 2.97075 3.61609 3.06259 2.79156 2.76589 2.94655 2.57771 4.76753 3.56330
2.68618 4.42225 2.77519 2.73123 3.46354 2.40513 3.72494 3.29354 2.67741 2.69355 4.24690 2.90347 2.73739 3.18146 2.89801 2.37887 2.77519 2.98518 4.58477 3.61503
0.11400 5.43890 2.26918 0.61958 0.77255 0.00000 *
1 2.84469 5.43592 3.17480 2.76604 4.73974 3.82086 2.84921 3.79498 2.55661 2.95708 2.50274 2.99752 3.37273 2.77536 2.08861 2.33124 2.32432 3.46807 5.89412 4.50954 1 r - - -
2.68618 4.42225 2.77519 2.73123 3.46354 2.40513 3.72494 3.29354 2.67741 2.69355 4.24690 2.90347 2.73739 3.18146 2.89801 2.37887 2.77519 2.98518 4.58477 3.61503
0.00721 5.33210 6.05445 0.61958 0.77255 0.37903 1.15367
2 2.56574 5.58242 2.92442 2.33486 4.92712 3.57653 4.03367 3.34225 2.02562 3.26845 4.62318 2.23324 3.17894 2.58384 2.54233 2.40058 2.79834 3.38823 6.01533 4.60460 2 k - - -
2.68618 4.42225 2.77519 2.73123 3.46354 2.40513 3.72494 3.29354 2.67741 2.69355 4.24690 2.90347 2.73739 3.18146 2.89801 2.37887 2.77519 2.98518 4.58477 3.61503
0.00658 5.42266 6.14500 0.61958 0.77255 0.44543 1.02318
3 1.37170 5.20503 3.33911 2.84075 4.41845 3.95135 4.16211 3.07174 2.99075 3.11149 3.93574 3.22883 3.05438 3.33495 2.96504 2.22852 2.50816 2.79614 5.72578 4.41195 3 a - - -
2.68618 4.42225 2.77519 2.73123 3.46354 2.40513 3.72494 3.29354 2.67741 2.69355 4.24690 2.90347 2.73739 3.18146 2.89801 2.37887 2.77519 2.98518 4.58477 3.61503
0.00647 5.43890 6.16124 0.61958 0.77255 0.48576 0.95510
(...)
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