A DB-type anvi’o artifact. This artifact is typically generated, used, and/or exported by anvi’o (and not provided by the user)..
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An anvi’o database that contains key information about the mapping of short reads from multiple samples to your contigs.
You can think of this as a extension of a contigs-db that contains information about how your contigs align with each of your samples. The vast majority of programs that use a profile database will also ask for the contigs database associated with it.
A profile database contains information about how short reads map to the contigs in a contigs-db. Specificially, for each sample, a profile database contains
This information is neccessary to run anvi’o programs like anvi-cluster-contigs, anvi-estimate-metabolism, and anvi-gen-gene-level-stats-databases. You can also interact with a profile database using programs like anvi-interactive.
Technically, “profile-db” refers to a profile database that contains the data from several samples – in other words, the result of running anvi-merge on several single-profile-db. However, since a single-profile-db has a lot of the functionality of a profile-db, it might be easier to think of a profile database as a header referring to both single-profile-dbs and profile-dbs (which can also be called a merged-profile-dbs). For simplicity sake, since most users are dealing with multiple samples, the name was shortened to just profile-db. The following are a list of differences in functionality between a single profile database and a merged profile database:
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